Theoretical studies

"Science is made with facts, as a house is made with stones: but an accumulation of facts is no more a science than a heap of stones is a house" (Henri Poincaré)

 

Conceptual thinking is often neglected by scientists for its excessive abstraction and its lack of use in the everyday life. However, theoretical framework or paradigms are indispensable in experimental science. They define the experimental ways to explore a natural phenomenon and give meaning to observations and data.

 

  • Based on interdisciplinary approach (immunology, microbiology, evolution theory, system theory), I tried to revisiting some dominant paradigms in immunology and evolutionary theory:

- Diversity Generator Mechanisms Are Essential Components of Biological Systems: The Two Queen Hypothesis.

https://www.frontiersin.org/articles/10.3389/fmicb.2018.00223/full

- The Unspecific Side of Acquired Immunity Against Infectious Disease: Causes and Consequences.

http://journal.frontiersin.org/article/10.3389/fmicb.2015.01525/full

- Generation of individual diversity: a too neglected fundamental property of adaptive immune system:

http://journal.frontiersin.org/article/10.3389/fimmu.2014.00208/full

- Redefining the Immune System as a Social Interface for Cooperative Processes:

http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003203

 

  • I also try to participate in a reflection on the regulation of scientific innovations and on the place of scientific knowledge in governance in the face of global threats:

- The Tragedy of Liberal Democratic Governance in the Face of Global Threats

https://www.frontiersin.org/articles/10.3389/fpubh.2022.902724/full

- Ethical control of innovation in a globalized and liberal world: Is good science still science?

https://www.sciencedirect.com/science/article/pii/S0160932719300146?via%3Dihub

Image
Image